Julie Hasenwinkel
Associate Professor, Program Director (Bioengineering)

Office: 359 Link Hall
Phone: (315) 443-3064
Email: jmhasenw@syr.edu
Personal Website: http://hasenwinkel.syr.edu


B.S.E., Biomedical Engineering, Duke University, 1992
M.S., Bioengineering, Clemson University, 1994
Ph.D., Biomedical Engineering, Northwestern University, 1999

Research Interests
Dr. Hasenwinkel's research interests are primarily focused on polymeric biomaterials for translational applications in nerve regeneration and orthopedics. Her laboratory is currently studying:

• The behavior of neuronal cells on mechanically-tuned hydrogel substrates with micropatterned surfaces
• Treatment of spinal cord injury by delivery of chondroitinase ABC and various neurotrophic factors to the injury site via incorporation in biodegradable nanoparticles
• Spatiotemporal changes in the micromechanical and biochemical properties of injured spinal cord tissue
• In vitro models of the glial scar
• Two-solution based bone cements for fixation of total joint prostheses and treatment of vertebral compression fractures

Dr. Hasenwinkel is also a member of the Syracuse Biomaterials Institute (www.biomaterials.syr.edu).

Teaching Interests
Biomaterials and Medical Devices, Advanced Biomechanics Laboratory, Tissue Engineering, Polymer Physics

Recent Publications
D.C. Rodrigues, J.L. Gilbert, J.M. Hasenwinkel, “Pseudoplasticity and setting properties of two-solution bone cement containing poly(methyl methacrylate) microspheres and nanospheres for kyphoplasty and vertebroplasty.” Journal of Biomedical Materials Research, Part B. Applied Biomaterials. 2009 Apr 22 (ePub ahead of print).

T.A. Saxena T, J.L. Gilbert JL, J.M. Hasenwinkel, “A versatile mesoindentation system to evaluate the micromechanical properties of soft, hydraged substrates on a cellular scale.” Journal of Biomedical Materials Research, Part A. 2008 Aug 5 (ePub ahead of print).

M.J. Allen, K.A. Leone, J.E. Schoonmaker, J.M. Hasenwinkel, and J.L. Gilbert, “Tissue response to in-situ polymerization of a new two-solution bone cement: Evaluation in a sheep model,” Journal of Biomedical Materials Research. Part B. Applied Biomaterials, 79(2):441-52, 2006.

T.W. Carone and J.M. Hasenwinkel, “Mechanical and morphological characterization of homogeneous and bi-layered poly(2-hydroxyethyl methacrylate) scaffolds for use in CNS regeneration,” Journal of Biomedical Materials Research. Part B. Applied Biomaterials, 78(2):247-82, 2006.

I.K. Merkhan and J.M. Hasenwinkel, “Quantitative analysis of monomer vapor release from two-solution bone cement by using a novel FTIR technique,” Journal of Biomedical Materials Research. Part B. Applied Biomaterials, 74(1):643-8, 2005.

J.B. Shim, S.J. Warner, J.M. Hasenwinkel, and J.L. Gilbert, “Analysis of the shelf-life of a two-solution bone cement,” Biomaterials, 26:4181-4187, 2005.

I.K. Merkhan, J.L. Gilbert, and J.M. Hasenwinkel, “Gentamicin release from two-solution and powder-liquid poly(methyl methacrylate)-based bone cements by using novel pH method,” Journal of Biomedical Materials Research, 69A(3):577-583, 2004.

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